Formulation and Product Development
Overview
For over a decade, we have worked tirelessly to explore Natural & Nature-similar health supplements that make life better. From the process development of energy-rich beverages to the manufacturing of the high values botanical extracts that are being referenced in pharmacopoeias and their finished formulation, we have been pioneers behind breakthroughs against some of humanity’s most stubborn and devastating health ailments.
Uniting our collective expertise with the creativity of research partners across the globe, we bring this same determination to our work today to keep finding ways to make human life better. This determination starts in the BioMylz’s research facility where BioMylz employees work to discover new process for formulating health supplements tweaking efficacy and controlled delivery of medicines, to discover new formulation processes that will help solve our world’s greatest health challenges.
Approach to R&D
Our approach to Research and Development – Timely Valued Healthcare Ingredients underscores the importance of creating value for our stakeholders. By accelerating the flow of such active substances and specific formulations leading to improved customer outcomes, we will shorten the duration of product delivery. Whether it’s a compound we are developing the process on our own or through a partnership, our priority is getting affordable high quality material in a timely manner and formulating them to the specific health needs.
Internal R&D
We recognize the importance of investing on our most valuable assets namely top-class eminent researchers who are working tirelessly to research and develop 'potential active natural medicinal ingredient' faster than ever before. We always strive to complement this work with the best research approach outside the company.
Primary focus is to deliver effective solutions in five main therapeutic areas: Bone health, Gut Health, skin health, blood sugar management, neuro/brain health, sports support, cardiac anti-oxidant, anti-inflammatory support. Today, our pipeline is comprised of more than 20 new phyto-therapeutic formulations.
What we are working on?
- Formulation development related process development for Enhancement of bioavailability & bioutilization of dietary Ingredients.
- Increasing long term stability of botanical active substances & animal natural molecules in the formulated products.
- Inclusiveness, exclusiveness of natural actives in the formulation to enhance the target action of complex biological molecules.
- Tweaking the formulations to eliminate restricted preservatives and other controlled excipients, as required by the respective country's health regulation & FDA guideline.
- Re-formulating the approved products into other physical Finished Dosage Forms to suit the convenience based on gender/ age/ race / social requirements.
How we work?
- R&D team will discuss with BioMylz's Business development team, customer's representative, customer's technical team for preliminary understanding of market requirement like product type, therapeutic segment, health application, dosage, product delivery form, target population, FDA compliance, Active molecular selection, stability requirement and other technical specifications.
- Prepare the sample in the form of oral solids, Liquid orals, topical cosmetics for 'product design approval' by the customer.
- Develop the tech packs, product dossiers, product registration documents with the support of regulatory & Quality team.
- Support the regulatory team to obtain the licences, certificates, clearances from domestic & international statutory bodies before technology transfer & scale-up production.
Current Research at BioMylz
Bio-active Substance:
- Standardization of Terpenes & Terpenoids
- Screening & Quantification of new Alkaloids from GRASS approved plant resources
- Comparative evaluation of Phyto-flavonoids / flavones, flavonols, Flavonals and their glycosides from whole plant & their standardised extracts for efficacy and target action.
- CoQ10 (Ubidecaranone)
- Yohimbine HCl
- Coleus Forscohlli
- Phyto-flavonoids
- Phyto-steroids
Herbal Extract Research output:
- Green tea - EGCG
- Green Coffee Bean Extract - Chlorogenic Acid
- Centella Asiatica - Asiaticoside
- Pomogranate extract
- Fenugreek - 4HIL
- Garcinia - HCA
- Morinda Citrifolia - Morindin
- Tribulus Terrestris -Protodioscin
- Horse Chest nut - Aescin
- Kalamegha- (Androgapholides)
- Tulsi - (Ursolic Acid)
- Neem - Azadirectin
- Amla - Gallic Acid
- Ginger - Gingerol
- Cinnamon
- Aloe Vera
- Garlic - Allicin/Allein
- Gymnema – Gymnemic Acid
- Bitter Guard – Charantine
- Sennoside
- Ashwagandha (Withanolides)
As part of the development process for active substances of both natural & synthetic origin, Biomylz and our partners sponsor clinical & toxicology studies to help determine safety and efficacy of health supplements; and with the intent of learning more about treatment options, disease states, diagnostics, and other associated issues that contribute to the health and well-being of consumers.
Collaborations
Research activity is in progress at affiliated University. We are also open to collaborate on multiple scientific areas of interest, scientific partnerships, Industry academia collaborations.
BIOMYLZ is proud to be a leader in Farmer-Ingredient processor-Industry partnerships and we are committed to bringing great minds together to help solve tough botanical & biotechnological challenges, accelerating breakthroughs for customers who need them, and increasing the efficiency and cost-effectiveness of bringing new segment of natural active substances and their formulated products to customers. Collaboration can bring together a wealth of knowledge and build upon existing science. This new model of investment helps streamline the discovery and development of new cost effective substances in a way that can get affordable treatments to people faster.